作业帮英语翻译Metabolic acidosis is a common complication in patients
来源：学生作业帮 编辑：作业帮 分类：综合作业 时间：2024/11/08 06:46:32
英语翻译
Metabolic acidosis is a common complication in patients with advanced chronic renal diseases and dialytic treatments are unable to correct it completely.In hemodialysis (HD) patients,severe metabolic acidosis is associated with an increased risk of death.Evidence from several experimental studies suggests that even mild metabolic acidosis is associated with systemic effects.Acidosis is implicated in endocrine changes and has negative repercussions on bone and protein metabolism.In addition,recent observations suggest that acidosis triggers inflammation and accelerates the progression of chronic kidney diseases.As a contradictory finding,acidosis can reduce circulating leptin.Clinical studies on the nutritional effects of metabolic acidosis correction have shown mildly favorable effects.Taking into account the systemic effects of metabolic acidosis it is suggested that even mild metabolic acidosis is corrected.However,the new findings concerning the systemic effects of acidosis must be evaluated in controlled trials.
Metabolic acidosis is a common complication in patients with advanced chronic renal diseases and dialytic treatments are unable to correct it completely.In hemodialysis (HD) patients,severe metabolic acidosis is associated with an increased risk of death.Evidence from several experimental studies suggests that even mild metabolic acidosis is associated with systemic effects.Acidosis is implicated in endocrine changes and has negative repercussions on bone and protein metabolism.In addition,recent observations suggest that acidosis triggers inflammation and accelerates the progression of chronic kidney diseases.As a contradictory finding,acidosis can reduce circulating leptin.Clinical studies on the nutritional effects of metabolic acidosis correction have shown mildly favorable effects.Taking into account the systemic effects of metabolic acidosis it is suggested that even mild metabolic acidosis is corrected.However,the new findings concerning the systemic effects of acidosis must be evaluated in controlled trials.
新陈代谢酸毒症是患有慢性肾脏疾病患者后期的常见并发症,并且透析疗法也无法完全予以矫正.在透析患者中,重度新陈代谢酸毒症会增加死亡的危险.几项试验研究的证据表明,即使是轻微的新陈代谢酸毒症也会对整个身体系统造成影响.酸毒症是因为内分泌的改变而造成的,并会对骨骼和蛋白新陈代谢机能造成反复的不良影响.另外,最近的观察表明,酸毒症会引发炎症并加速慢性肾病的恶化程度.作为一个矛盾的研究结果,酸毒症可以减少循环瘦蛋白.针对新陈代谢酸毒症矫正对营养效果的临床研究显示少许良性影响.考虑到新陈代谢酸毒症对整个身体系统的影响,故此建议即使是轻微的新陈代谢酸毒症也应当予以矫正.尽管如此,有关酸毒症对整个身体系统影响的新发现必须在经过控制的试验治疗中予以评估.
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