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--the patient lokks much better .__what_ is it that has made

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--the patient lokks much better .__what_ is it that has made him __what__he is today?
-- Perhaps the special medicine and his family's patient care.
A.What; thatB.That; thatC.What; whatD.That; what为什么选C?
第一个what是特殊疑问词作主语
第二个what是引导宾语从句的连词,what he is today,他现在的样子,而且what在从句中充当he is后的表语
简化为:what has made him what he is today?is it that是强调句的基本结构词,当特殊疑问词what被强调时强调结构it is...that...要变为疑问语序what is it that...