英语翻译These analogs have IC50s against purified MEK-1 enzyme i
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英语翻译
These analogs have IC50s against purified MEK-1 enzyme in the range of 0.4-10 μm,with IC50s against other kinases (e.g.Erk,Raf,PKC) that were 10- to 200-fold higher and thus form a new class of MEK-1 inhibitors.Therefore,the present study was undertaken to determine the cytotoxic and cell cycle regulatory effects of such a compound on human prostate cancer cell lines.
These analogs have IC50s against purified MEK-1 enzyme in the range of 0.4-10 μm,with IC50s against other kinases (e.g.Erk,Raf,PKC) that were 10- to 200-fold higher and thus form a new class of MEK-1 inhibitors.Therefore,the present study was undertaken to determine the cytotoxic and cell cycle regulatory effects of such a compound on human prostate cancer cell lines.
这些类似物具有IC50s来抵御0.4-10微米的纯化MEK-1酶. 随着IC50s抵御其他的10到200倍高的激酶,就形成了一种新的MKE-1抑制剂的类别.因此,当前执行的的研究来决定这种化合物的细胞霉素和细胞周期规则对人类前列腺癌细胞系的影响.
外行,不懂啥意思
外行,不懂啥意思
英语翻译These analogs have IC50s against purified MEK-1 enzyme i
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