作业帮英语翻译Organometallic chemistry,biology and medicine:ruthenium
来源：学生作业帮 编辑：作业帮 分类：英语作业 时间：2024/11/05 19:03:20
英语翻译
Organometallic chemistry,biology and medicine:ruthenium arene anticancer complexes
摘要:Our work has shown that certain ruthenium(II) arene complexes exhibit promising anticancer activity in vitro and in vivo.The complexes are stable and water-soluble,and their frameworks provide considerable scope for optimising the design,both in terms of their biological activity and for minimising side-effects by variations in the arene and the other coordinated ligands.Initial studies on amino acids and nucleotides suggest that kinetic and thermodynamic control over a wide spectrum of reactions of Ru(II) arene complexes with biomolecules can be achieved.These Ru( II) arene complexes appear to have an altered profile of biological activity in comparison with metal-based anticancer complexes currently in clinical use or on clinical trial.
Organometallic chemistry,biology and medicine:ruthenium arene anticancer complexes
摘要:Our work has shown that certain ruthenium(II) arene complexes exhibit promising anticancer activity in vitro and in vivo.The complexes are stable and water-soluble,and their frameworks provide considerable scope for optimising the design,both in terms of their biological activity and for minimising side-effects by variations in the arene and the other coordinated ligands.Initial studies on amino acids and nucleotides suggest that kinetic and thermodynamic control over a wide spectrum of reactions of Ru(II) arene complexes with biomolecules can be achieved.These Ru( II) arene complexes appear to have an altered profile of biological activity in comparison with metal-based anticancer complexes currently in clinical use or on clinical trial.
有机金属化学、生物学和医学:钌芳烃抗癌复合物
我们的研究已经表明,某些钌(II)芳烃抗癌活性复合物展现出在试管内和活体内的抗癌作用的可能性.这种复合物稳定且具有水溶性,他们的结构提供了优化设计的余地,无论是在其生物活性,还是通过芳烃的变化减少副作用和其他协调配体（配合基）方面.初步关于氨基酸和核苷酸的研究表明,在动力学和热力学上在大范围控制钌( II) 芳烃复合物对大生物分子的反应可以实现.这些钌( II) 芳烃复合物似乎在临床使用或临床试验上与目前基于金属抗癌的复合物相比有改变生物活性的作用.
非化学专业有的东西不懂,都是一点点查的,希望对你有帮助
我们的研究已经表明,某些钌(II)芳烃抗癌活性复合物展现出在试管内和活体内的抗癌作用的可能性.这种复合物稳定且具有水溶性,他们的结构提供了优化设计的余地,无论是在其生物活性,还是通过芳烃的变化减少副作用和其他协调配体（配合基）方面.初步关于氨基酸和核苷酸的研究表明,在动力学和热力学上在大范围控制钌( II) 芳烃复合物对大生物分子的反应可以实现.这些钌( II) 芳烃复合物似乎在临床使用或临床试验上与目前基于金属抗癌的复合物相比有改变生物活性的作用.
非化学专业有的东西不懂,都是一点点查的,希望对你有帮助
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